Loquat Leaf Extract Ursolic Acid

This extract is typically standardized to contain 25-98% ursolic acid. It has antioxidant, anti-inflammatory, and anti-cancer properties. Ursolic acid is usually detected using HPLC.

Botanical Source: Loquat (Eriobotrya japonica)

Extract Part: Leaves

Extraction Type: Standardized extract

Extraction Method: Soxhlet extraction

Extraction Solvent: Ethanol

Detection Method: HPLC

Grade: Pharmaceutical grade

Odor: Odorless

Color: White to off-white powder

Appearance: Fine crystalline powder

CAS Number: 77-52-1

Molecular Formula: C30H48O3

Molecular Weight: 456.7 g/mol

Pharmacological Properties

1. Antioxidant properties: Ursolic acid has been shown to have antioxidant properties, which help protect cells from oxidative stress and damage caused by free radicals. It achieves this by scavenging free radicals and increasing the activity of antioxidant enzymes in the body. Studies have shown that Ursolic acid can prevent lipid peroxidation, reduce the levels of reactive oxygen species (ROS) and increase the activity of antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT) in cells.

2. Anti-inflammatory properties: Ursolic acid has been shown to have potent anti-inflammatory properties, which can help reduce inflammation and associated pain. It achieves this by inhibiting the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), and the activity of cyclooxygenase-2 (COX-2) enzyme. Ursolic acid has also been shown to reduce the levels of inflammatory markers in animal models of acute and chronic inflammation.

3. Anticancer properties: Ursolic acid has been shown to have potent anticancer properties, which make it a promising candidate for cancer prevention and therapy. It achieves this by inhibiting cell proliferation, inducing apoptosis, and suppressing angiogenesis and metastasis. Ursolic acid has been shown to have anti-cancer effects against a wide range of cancers, including lung, colon, breast, prostate, and pancreatic cancer.

4. Anti-diabetic properties: Ursolic acid has been shown to have anti-diabetic properties, which make it a promising candidate for the prevention and management of diabetes. It achieves this by improving insulin sensitivity, increasing glucose uptake in skeletal muscles, and reducing hepatic gluconeogenesis. Ursolic acid has also been shown to reduce the levels of blood glucose and glycosylated hemoglobin (HbA1c) in animal models of diabetes.

5. Anti-cachexia properties: Ursolic acid has been shown to have anti-cachexia properties, which make it a promising candidate for the prevention and management of muscle wasting associated with various diseases such as cancer, AIDS, and sepsis. It achieves this by reducing muscle atrophy and increasing muscle mass and strength. Ursolic acid has also been shown to improve exercise endurance and physical performance in animal models.

Applications

1. Health and Wellness Industry:

With a growing demand for natural remedies and health products, Loquat Leaf Extract Ursolic Acid has emerged as a valuable ingredient. Its antioxidant and anti-inflammatory properties make it an attractive option for dietary supplements, herbal medicines, and functional food products. The extract is known for its potential to enhance immunity, protect the liver, lower blood pressure, and regulate blood sugar levels, making it a sought-after component in various health formulations.

2. Cosmetics and Skincare:

The cosmetic industry has embraced the beneficial properties of Loquat Leaf Extract Ursolic Acid. As an ingredient in skincare products, it aids in reducing skin inflammation, improving elasticity, and promoting collagen production. The extract's antioxidant nature also helps in combating free radicals, reducing the signs of aging, and maintaining healthy, youthful skin. With its natural and sustainable appeal, Loquat Leaf Extract Ursolic Acid is gaining popularity as a key ingredient in natural and organic cosmetic formulations.

3. Agricultural and Animal Husbandry:

Loquat Leaf Extract Ursolic Acid has shown promise in agricultural practices and animal husbandry. When incorporated into animal feed, it has demonstrated the potential to improve animal health and enhance productivity. Additionally, it has been observed to possess antimicrobial properties that can combat common pathogens in livestock. Furthermore, its usage in crop production has shown positive effects on plant growth, disease resistance, and yield improvement.

4. Food and Beverage Industry:

The food and beverage industry is exploring the incorporation of Loquat Leaf Extract Ursolic Acid in various products. As a natural food additive and flavor enhancer, it provides health benefits alongside a unique taste profile. This extract is also being used to develop natural sweeteners, juice powders, and colorants, offering a healthier alternative to artificial additives. Furthermore, it has been observed to have applications in preserving food quality and extending shelf life.

5. Nutraceuticals and Functional Foods:

The nutraceutical and Functional Food sectors have recognized the potential of Loquat Leaf Extract Ursolic Acid in developing innovative and health-focused products. Its bioactive compounds contribute to the formulation of dietary supplements, herbal teas, and functional beverages. By harnessing its beneficial properties, manufacturers can cater to the increasing consumer demand for natural and holistic health solutions.

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